Hi Juan. Support suggested me the case I haven't thought before) So I've found a way to make it working. And now I am here to inform you that I've finished: Price-Optimizer now can handle variations! Please take a look. Remember to desetup & setup first in order to apply fresh changes.
As usual: in case of any question or issue - please let me know.

I am not quite sure I got your point right: what do you mean by "can't setup"? Please clarify: do you see any errors - or just see that the effect of price optimization is not applied?

I've checked your installation: the store marked as setup, the products are handled correctly. The only thing I've discovered is the problem in how the application reacts on product's changes: in some cases it wasn't able to create required product options. Now this behavior is fixed.
Please setup (desetup first if needed) the application using your dashboard - could you? Now it's fine or not?

In case of any questions - feel free to respond to this topic or start a new one.
Thanks for your feedback once more, Sonia.

Sorry for late response - my notification settings were misconfigured.
In theory - yes, there could be such option to directly install. But the application uses Ecwid billing and tightly integrated with it. To pass around Ecwid billing I need to install (or develop) separate billing system. Otherwise it would be impossible to handle all of the billing-cases manually.
So the answer is: sorry, at the moment it's not possible, it's too hard to implement.